RED1 Antikörper (AA 6-66)

Produktnummer ABIN264972

Produktdetails anti-RED1 Antikörper

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Bindungsspezifität: AA 6-66

Reaktivität: Ratte

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser RED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).

Aufreinigung: Purified

Immunogen: GST fusion protein containing aa 6-66 of the rat RED1 coding sequence

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 1000. POSITIVE CONTROL: Rat Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Referenzen für anti-RED1 Antikörper (ABIN264972)

Yamashita, Chai, Teramoto, Tsuji, Shimazaki, Muramatsu, Kwak: "Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1710-9, (2013) (PubMed).

Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).

Details zu RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Andere Bezeichnung: ADARB1 / ADAR2 (ADARB1 Produkte)

Synonyme: ADARB1 antikoerper, RED1 antikoerper, ADAR2 antikoerper, DRABA2 antikoerper, DRADA2 antikoerper, 1700057H01Rik antikoerper, AW124433 antikoerper, AW558573 antikoerper, Adar2 antikoerper, BB220382 antikoerper, D10Bwg0447e antikoerper, Red1 antikoerper, adar2 antikoerper, adarb1 antikoerper, red1 antikoerper, adenosine deaminase, RNA specific B1 antikoerper, adenosine deaminase, RNA-specific, B1 antikoerper, adenosine deaminase, RNA-specific, B1 L homeolog antikoerper, adenosine deaminase, RNA-specific, B1a antikoerper, ADARB1 antikoerper, adarb1 antikoerper, adarb1.L antikoerper, Adarb1 antikoerper, adarb1a antikoerper

Hintergrund: RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.Synonyms: DRADA2, Double-stranded RNA-specific editase 1, RED1, RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase

Molekulargewicht: 80.7 kDa

Gen-ID: 25367

NCBI Accession: NP_001104525

UniProt: P51400