KRT16
Reaktivität: Human
IHC, StM
Wirt: Maus
Monoclonal
LL025
unconjugated
Applikationshinweise
ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Yu, Ye, Zhong, Ding, Chen: "Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model." in: Orthopaedic surgery, Vol. 7, Issue 2, pp. 161-7, (2016) (PubMed).
Zhang, Han, Song, Luo, Jin, Mu, Su, Ji, Ren, Liu: "Interferon-? regulates the function of mesenchymal stem cells from oral lichen planus via indoleamine 2,3-dioxygenase activity." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 44, Issue 1, pp. 15-27, (2015) (PubMed).
Suga, Sugimura, Koshiishi, Yorifuji, Makino, Takeda: "Heparin/heparan sulfate/CD44-v3 enhances cell migration in term placenta-derived immortalized human trophoblast cells." in: Biology of reproduction, Vol. 86, Issue 5, pp. 134, 1-8, (2012) (PubMed).
CK16 antikoerper, FNEPPK antikoerper, K16 antikoerper, K1CP antikoerper, KRT16A antikoerper, NEPPK antikoerper, AI324768 antikoerper, Krt1-16 antikoerper, Ka16 antikoerper, KRT16 antikoerper, Krt16 antikoerper, keratin 16 antikoerper, keratin 16, type I S homeolog antikoerper, keratin, type I cytoskeletal 16 antikoerper, KRT16 antikoerper, Krt16 antikoerper, krt16.S antikoerper, LOC101108147 antikoerper, LOC100714013 antikoerper
Hintergrund
Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10 % of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. Two cytokeratins, 6 and 16, are expressed when keratincytes are undergoing rapid turnover in various pathological states, wound healing, psoriasis and some carcinomasSynonyms: CK16, Cytokeratin-16, K16, KRT16, KRT16A, Keratin 16, Keratin type I cytoskeletal 16, Keratin-16