The antibody was purified by affinity chromatography.
Sterilität
0.22 μm filtered
Klon
1Y26
Isotyp
IgG1
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
0.22 μm filtered protein solution is in PBS, pH 7.2.
Handhabung
Avoid freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20°C.
Target
RPII33
(RNA Polymerase II 33kD Subunit (RPII33))
Andere Bezeichnung
RNA Polymerase II RPB3
Substanzklasse
Chemical
Hintergrund
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The RNA polymermase II subunit RPB3 is a component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft and is known to be involved in transcription termination.