CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Reaktivität
Maus
Wirt
Hamster
Klonalität
Monoklonal
Konjugat
Dieser CD137 Antikörper ist konjugiert mit APC
Applikation
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
CDw137 is a 39 kD TNF-receptor superfamily member also known as 4-1BB, TNFRSF9, Ly-63, and ILA (Induced by Lymphocyte Activation). CDw137 is expressed as monomers, dimers, and tetramers on activated T and B cells. Interaction of CDw137 with its ligand, 4-1BBL (CDw137L), is important in T-B cell costimulation. The 17B5 antibody has been reported to block 4-1BBL costimulated T cell proliferation.