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IL17 Receptor B Antikörper (Alexa Fluor 647)
IL17RB
Reaktivität: Maus
FACS
Wirt: Ratte
Monoclonal
9B10
Alexa Fluor 647
Produktnummer ABIN2657212
Produktdetails anti-IL17 Receptor B Antikörper (Alexa Fluor 647)
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Target
Alle IL17 Receptor B (IL17RB) Antikörper anzeigen
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Reaktivität
Alle Reaktivitäten für IL17 Receptor B Antikörper
Maus
Wirt
Alle Wirte für IL17 Receptor B Antikörper
Ratte
Klonalität
Alle Klonalitäten für IL17 Receptor B Antikörper
Monoklonal
Konjugat
Alle Konjugate für IL17 Receptor B Antikörper
Dieser IL17 Receptor B Antikörper ist konjugiert mit Alexa Fluor 647
Applikation
Alle Applikationen für IL17 Receptor B Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Klon
9B10
Isotyp
IgG2a kappa
Top Product
Discover our top product IL17RB Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C
Details zu IL17 Receptor B
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Target
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Andere Bezeichnung
IL-17RB (IL17RB Produkte )
Synonyme
IL17RB antikoerper, CRL4 antikoerper, EVI27 antikoerper, IL17BR antikoerper, IL17RH1 antikoerper, Evi27 antikoerper, IL-17ER antikoerper, IL-17Rh1 antikoerper, Il17br antikoerper, interleukin 17 receptor B antikoerper, IL17RB antikoerper, Il17rb antikoerper
Hintergrund
IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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