×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
CD8 alpha Antikörper (Alexa Fluor 488)
CD8A
Reaktivität: Maus
FACS, IHC, IP, IF, BR
Wirt: Ratte
Monoclonal
53-6-7
Alexa Fluor 488
Produktnummer ABIN2657489
Produktdetails anti-CD8 alpha Antikörper (Alexa Fluor 488)
(ausblenden)
Target
Alle CD8 alpha (CD8A) Antikörper anzeigen
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Reaktivität
Alle Reaktivitäten für CD8 alpha Antikörper
Maus
Wirt
Alle Wirte für CD8 alpha Antikörper
Ratte
Klonalität
Alle Klonalitäten für CD8 alpha Antikörper
Monoklonal
Konjugat
Alle Konjugate für CD8 alpha Antikörper
Dieser CD8 alpha Antikörper ist konjugiert mit Alexa Fluor 488
Applikation
Alle Applikationen für CD8 alpha Antikörper
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Klon
53-6-7
Isotyp
IgG2a kappa
Top Product
Discover our top product CD8A Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C
Details zu CD8 alpha
(ausblenden)
Target
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Andere Bezeichnung
CD8a (CD8A Produkte )
Synonyme
cd8 antikoerper, LOC100136450 antikoerper, BB154331 antikoerper, Ly-2 antikoerper, Ly-35 antikoerper, Ly-B antikoerper, Lyt-2 antikoerper, zgc:136643 antikoerper, CD8 antikoerper, Leu2 antikoerper, MAL antikoerper, p32 antikoerper, RHACD8-4 antikoerper, CD8a molecule antikoerper, uncharacterized LOC100125537 antikoerper, CD8 alpha antikoerper, CD8 antigen, alpha chain antikoerper, T-cell surface glycoprotein CD8 alpha chain antikoerper, Cd8a antikoerper, LOC100125537 antikoerper, LOC100136450 antikoerper, CD8A antikoerper, cd8a antikoerper, LOC100126556 antikoerper
Hintergrund
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Pathways
T-Zell Rezeptor Signalweg
Zuletzt angesehen
(ausblenden)