Dieser CD40 Ligand Antikörper ist konjugiert mit Alexa Fluor 647
Applikation
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Blocking Reagent (BR), Cytometry by Time of Flight (CyTOF)
Kreuzreaktivität
Cynomolgus, Rhesusaffen
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.