Sialoadhesin/CD169 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657651

Produktdetails anti-Sialoadhesin/CD169 Antikörper (Alexa Fluor 647)

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Sialoadhesin/CD169 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: ELISA

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Klon: 7-239

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu Sialoadhesin/CD169

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Andere Bezeichnung: CD169 (SIGLEC1 Produkte)

Synonyme: Cd169 antikoerper, Siglec-1 antikoerper, Sn antikoerper, CD169 antikoerper, SIGLEC-1 antikoerper, SN antikoerper, dJ1009E24.1 antikoerper, SA antikoerper, SIGLEC1 antikoerper, p210 antikoerper, pSn antikoerper, sialic acid binding Ig like lectin 1 antikoerper, sialic acid binding Ig-like lectin 1, sialoadhesin antikoerper, SIGLEC1 antikoerper, Siglec1 antikoerper

Hintergrund: CD169, also known as Siglec-1 and Sialoadhesin (Sn), is a 210 kD type I single membrane-spanning glycoprotein. It is the largest member of the Siglec family, consisting of 1709 amino acids and belonging to the immunoglobulin superfamily. CD169 is expressed by macrophages and dendritic cells. By its affinity to α2,3-linked sialic acid, it is involved in macrophage binding to different cell types such as granulocytes, monocytes, NK, B and T cells. Several CD169 counter receptors, such as CD227 on human breast cancer cells, CD43 on T cells and CD206 on macrophages, have been reported.