GP5 Antikörper (APC)

Produktnummer ABIN2658230

Produktdetails anti-GP5 Antikörper (APC)

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Reaktivität: Maus, Ratte

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser GP5 Antikörper ist konjugiert mit APC

Applikation: Intracellular Flow Cytometry (ICFC)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Klon: 1C2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu GP5

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Andere Bezeichnung: CD42d (GP5 Produkte)

Synonyme: lib antikoerper, GPV antikoerper, PLGPV antikoerper, CD42d antikoerper, glycoprotein V platelet L homeolog antikoerper, glycoprotein V platelet antikoerper, glycoprotein 5 (platelet) antikoerper, glycoprotein V (platelet) antikoerper, gp5.L antikoerper, GP5 antikoerper, Gp5 antikoerper

Hintergrund: CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.