LAG3 Antikörper (Biotin)
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- Target Alle LAG3 Antikörper anzeigen
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser LAG3 Antikörper ist konjugiert mit Biotin
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- Klon
- C9B7W
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product LAG3 Primärantikörper
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anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibody
LAG3 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21775 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) antibodyLAG3 Reaktivität: Human WB, ELISA, IHC, FACS, ICC, Neut Wirt: Maus Monoclonal 3A4A10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 8B12E10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (N-Term) antibodyLAG3 Reaktivität: Human WB, ELISA, IHC, FACS, ICC, IP Wirt: Maus Monoclonal L4-PL33 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibodyLAG3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 244-487) antibodyLAG3 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibodyLAG3 Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibodyLAG3 Reaktivität: Human, Maus WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Andere Bezeichnung
- CD223 (LAG3 Produkte)
- Synonyme
- CD223 antikoerper, LAG-3 antikoerper, Ly66 antikoerper, lymphocyte activating 3 antikoerper, lymphocyte-activation gene 3 antikoerper, LAG3 antikoerper, Lag3 antikoerper
- Hintergrund
- CD223, also known as LAG-3, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. It is the gene product of lymphocyte activation gene-3 (Lag3) with structural similarity to CD4. CD223 is expressed on activated T cells and NK cells, as well as T regulatory cells. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. In association with the CD3 complex, CD223 has been shown as a negative regulatory molecule to inhibit TCR-mediated signaling and regulate homeostatic T cell expansion. In contrast to inhibition, CD223 has an activation function to promote immune responses by inducing MHC class II signaling in antigen presenting cells.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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