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- Target Alle ITGA4 Antikörper anzeigen
- ITGA4 (Integrin alpha 4 (ITGA4))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA4 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität
- Pavian, Schimpanse, Marmoset, Cynomolgus, Rhesusaffen, Squirrel Monkey (Saimiri spec.), Pferd, Rind (Kuh), Schaf, Hund, Katze
- Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.
- Klon
- 9F10
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product ITGA4 Primärantikörper
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anti-Integrin alpha 4 (ITGA4) (Internal Region) antibody
ITGA4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 551-650) antibodyITGA4 Reaktivität: Human, Maus, Kaninchen FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 833-977) antibodyITGA4 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 7E4C5 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 376-558) antibodyITGA4 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (C-Term) antibodyITGA4 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human FACS, WB, EIA Wirt: Maus Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Maus FACS, IP, IHC (fro) Wirt: Ratte Monoclonal R1-2 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Maus FACS, IP, IHC (fro) Wirt: Ratte Monoclonal DATK32 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- ITGA4 (Integrin alpha 4 (ITGA4))
- Andere Bezeichnung
- CD49d (ITGA4 Produkte)
- Synonyme
- CD49D antikoerper, IA4 antikoerper, LOC100219853 antikoerper, integrin subunit alpha 4 antikoerper, integrin alpha 4 antikoerper, integrin subunit alpha 4 S homeolog antikoerper, ITGA4 antikoerper, Itga4 antikoerper, itga4.S antikoerper
- Hintergrund
- CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
- Pathways
- Integrin Complex
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