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KLRA1 Antikörper (FITC)
KLRA1
Reaktivität: Maus
FACS
Wirt: Ratte
Monoclonal
YE1-48-10-6
FITC
Produktnummer ABIN2661960
Produktdetails anti-KLRA1 Antikörper (FITC)
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Target
Alle KLRA1 Antikörper anzeigen
KLRA1
(Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
Reaktivität
Alle Reaktivitäten für KLRA1 Antikörper
Maus
Wirt
Alle Wirte für KLRA1 Antikörper
Ratte
Klonalität
Alle Klonalitäten für KLRA1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für KLRA1 Antikörper
Dieser KLRA1 Antikörper ist konjugiert mit FITC
Applikation
Alle Applikationen für KLRA1 Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Klon
YE1-48-10-6
Isotyp
IgG2a kappa
Top Product
Discover our top product KLRA1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu KLRA1
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Target
KLRA1
(Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
Andere Bezeichnung
Ly-49A (KLRA1 Produkte )
Synonyme
Klra2 antikoerper, Ly49i8 antikoerper, A1 antikoerper, Klra22 antikoerper, Ly49a antikoerper, Ly49o<129> antikoerper, Ly49v antikoerper, LY49 antikoerper, KLRA1 antikoerper, Ly49 antikoerper, killer cell lectin-like receptor, subfamily A, member 1 antikoerper, killer cell lectin-like receptor subfamily A, member 1 antikoerper, Klra1 antikoerper, KLRA1 antikoerper, LY49 antikoerper
Hintergrund
Ly-49A is a 44 kD member of the C-type lectin/Ly-49 family proteins. It is a type-II transmembrane, disulfide-linked homodimer with C-type lectin extracellular domains. Ly-49A is present on a subset of NK and NK-T cells. Ly-49A, like other members of this family, inhibits NK cell activation through the recognition and interaction of certain MHC class I haplotypes on potential target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk, triggering phosphorylation of the ITIM motif in the cytoplasmic domain and recruitment of SHP-1 and SHP-2. The YE1/48.10.6 antibody reacts with NK cells from all mouse strains tested and reverses the inhibition of NK cytotoxicity.
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