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IKZF3 Antikörper (PE)

IKZF3 Reaktivität: Maus FACS Wirt: Maus Monoclonal 8B2 PE
Produktnummer ABIN2662381
  • Target Alle IKZF3 Antikörper anzeigen
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    Reaktivität
    • 66
    • 36
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 55
    • 14
    Maus
    Klonalität
    • 56
    • 13
    Monoklonal
    Konjugat
    • 36
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IKZF3 Antikörper ist konjugiert mit PE
    Applikation
    • 58
    • 27
    • 13
    • 13
    • 10
    • 9
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Keine Kreuzreaktivität
    Maus
    Aufreinigung
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Klon
    8B2
    Isotyp
    IgG1 kappa, IgG
    Top Product
    Discover our top product IKZF3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    Andere Bezeichnung
    Aiolos (IKZF3 Produkte)
    Synonyme
    AIO antikoerper, AIOLOS antikoerper, ZNFN1A3 antikoerper, aio antikoerper, aiolos antikoerper, znfn1a3 antikoerper, IKZF3 antikoerper, 5830411O07Rik antikoerper, Aiolos antikoerper, Zfpn1a3 antikoerper, Znfn1a3 antikoerper, IKAROS family zinc finger 3 antikoerper, IKAROS family zinc finger 3 L homeolog antikoerper, IKZF3 antikoerper, ikzf3.L antikoerper, Ikzf3 antikoerper
    Hintergrund
    Aiolos, an Ikaros family member, is also known as Izkf3. It has a molecular weight of 58 kD and shows 70 % homology to the Ikaros isoform, Ik-1, particularly in the DNA binding and C-terminal domains. Aiolos can form a heteromer with Ikaros or exist as a homodimer. The homomeric complex is a potent transcriptional activator. Unlike Ikaros, Aiolos is expressed in late fetal thymus and adult lymphoid organs. Among the adult hematopoietic progenitors, Aiolos is expressed at low levels in mulitpotent but not in pluripotent stem cells. When these multipotent progenitors become more restricted to T and B lymphoid pathways there is an upregulation in Aiolos expression. The highest expression of Aiolos is detected in the spleen (especially in B-cells) followed by thymus and bone marrow, and cannot be detected in the non-lymphoid organs. Aiolos plays an important role in lymphocyte proliferation and differentiation.
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