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IGF1R Antikörper (PE)
IGF1R
Reaktivität: Human
IHC, FACS, Dep
Wirt: Maus
Monoclonal
1H7-CD221
PE
Produktnummer ABIN2662549
Produktdetails anti-IGF1R Antikörper (PE)
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Target
Alle IGF1R Antikörper anzeigen
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Reaktivität
Alle Reaktivitäten für IGF1R Antikörper
Human
Wirt
Alle Wirte für IGF1R Antikörper
Maus
Klonalität
Alle Klonalitäten für IGF1R Antikörper
Monoklonal
Konjugat
Alle Konjugate für IGF1R Antikörper
Dieser IGF1R Antikörper ist konjugiert mit PE
Applikation
Alle Applikationen für IGF1R Antikörper
Immunohistochemistry (IHC), Flow Cytometry (FACS), Depletion (Dep)
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Klon
1H7-CD221
Isotyp
IgG1 kappa
Top Product
Discover our top product IGF1R Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu IGF1R
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Target
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Andere Bezeichnung
CD221 (IGF1R Produkte )
Synonyme
CMT2N antikoerper, CD221 antikoerper, IGFIR antikoerper, IGFR antikoerper, JTK13 antikoerper, IGFIRC antikoerper, IGFR1 antikoerper, IGF-1R antikoerper, IGF1R antikoerper, DKFZp469I0618 antikoerper, igf-1r antikoerper, xIGF-1R antikoerper, xIGFR antikoerper, xigf1r antikoerper, A330103N21Rik antikoerper, D930020L01 antikoerper, hyft antikoerper, igf-ir antikoerper, IGF-IR antikoerper, IGF-IRb antikoerper, wu:fb03h06 antikoerper, IGF-IRa antikoerper, sb:eu1090 antikoerper, wu:fi20b10 antikoerper, alanyl-tRNA synthetase antikoerper, insulin like growth factor 1 receptor antikoerper, insulin-like growth factor 1 receptor antikoerper, insulin-like growth factor 1 antikoerper, insulin-like growth factor I receptor antikoerper, insulin like growth factor 1 receptor S homeolog antikoerper, insulin-like growth factor 1b receptor antikoerper, insulin-like growth factor 1a receptor antikoerper, AARS antikoerper, IGF1R antikoerper, Igf1r antikoerper, igf1r antikoerper, Igf1 antikoerper, LOC780503 antikoerper, LOC100136427 antikoerper, igf1r.S antikoerper, igf1rb antikoerper, igf1ra antikoerper
Hintergrund
CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies reveal its function of recruiting immune cells during tissue repair.
Pathways
RTK Signalweg , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagie
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