The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
MGC179455 antikoerper, CLL-1 antikoerper, CLL1 antikoerper, DCAL-2 antikoerper, MICL antikoerper, D230024O04 antikoerper, KLRL1 antikoerper, Micl antikoerper, C-type lectin domain family 12 member A antikoerper, C-type lectin domain family 12, member a antikoerper, C-type lectin domain family 12, member A antikoerper, CLEC12A antikoerper, Clec12a antikoerper
Hintergrund
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8 + dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.