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TREML2 Antikörper (PE)

TREML2 Reaktivität: Human FACS Wirt: Maus Monoclonal MIH60 PE
Produktnummer ABIN2662891
  • Target Alle TREML2 Antikörper anzeigen
    TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
    Reaktivität
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 12
    • 2
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 14
    • 3
    Monoklonal
    Konjugat
    • 11
    • 2
    • 2
    • 1
    • 1
    Dieser TREML2 Antikörper ist konjugiert mit PE
    Applikation
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Klon
    MIH60
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product TREML2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
    Andere Bezeichnung
    TLT-2 (TREML2 Produkte)
    Synonyme
    TREM-B2V1 antikoerper, C6orf76 antikoerper, TLT-2 antikoerper, TLT2 antikoerper, dJ238O23.1 antikoerper, AW049306 antikoerper, Gm750 antikoerper, Tlt2 antikoerper, triggering receptor expressed on myeloid cells like 2 antikoerper, triggering receptor expressed on myeloid cells-like 2 antikoerper, TREML2 antikoerper, Treml2 antikoerper
    Hintergrund
    Trem-like transcript 2 protein (TLT2), also known as TREML2, is a 33 kD (unglycosylated) type I transmembrane protein with a single IgV domain contains two potential N-glycosylation sites, a serine/threonine-rich region with numerous predicted O-linked glycosylation sites, a single membrane-spanning region, and a short cytoplasmic tail. TLT2 is expressed on B lineage cells, macrophages, neutrophils in bone marrow and periphery, and the expression level can be upregulated in response to inflammation. As a receptor, TLT2 likely plays a role in innate immunity. Recent studies have demonstrated that ligation of TLT2 inhibits the oxidative burst in neutrophils upon fMLP stimulation, indicating that TLT2 may function as an inhibitory receptor that attenuates activation of neutrophils, and possibly macrophages. Recently TLT-2 protein has been found on CD8+ T cells and is induced on activated CD4+ T cells.
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