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CSF1R Antikörper
CSF1R
Reaktivität: Maus
IP, ICFC
Wirt: Ratte
Monoclonal
AFS98
unconjugated
Produktnummer ABIN2664137
Produktdetails anti-CSF1R Antikörper
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Target
Alle CSF1R Antikörper anzeigen
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Reaktivität
Alle Reaktivitäten für CSF1R Antikörper
Maus
Wirt
Alle Wirte für CSF1R Antikörper
Ratte
Klonalität
Alle Klonalitäten für CSF1R Antikörper
Monoklonal
Konjugat
Alle Konjugate für CSF1R Antikörper
Dieser CSF1R Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CSF1R Antikörper
Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
AFS98
Isotyp
IgG2a kappa
Top Product
Discover our top product CSF1R Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu CSF1R
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Target
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Andere Bezeichnung
CD115 (CSF1R Produkte )
Synonyme
AI323359 antikoerper, CD115 antikoerper, CSF-1R antikoerper, Csfmr antikoerper, Fim-2 antikoerper, Fms antikoerper, M-CSF-R antikoerper, M-CSFR antikoerper, C-FMS antikoerper, CSFR antikoerper, FIM2 antikoerper, FMS antikoerper, HDLS antikoerper, PDGFRB antikoerper, MGC89146 antikoerper, CSF-1-R antikoerper, c-fms antikoerper, mrfms antikoerper, CSF1 antikoerper, M-CSF antikoerper, csf1r antikoerper, fms antikoerper, panther antikoerper, colony stimulating factor 1 receptor antikoerper, macrophage colony-stimulating factor receptor antikoerper, colony stimulating factor 1 receptor, a antikoerper, Csf1r antikoerper, CSF1R antikoerper, m-csfr antikoerper, csf1r antikoerper, csf1ra antikoerper
Hintergrund
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
Pathways
RTK Signalweg , Inositol Metabolic Process , Cell-Cell Junction Organization
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