Fc Receptor, IgG, Low Affinity IV (FCGR4) Antikörper

Produktnummer ABIN2664272

Produktdetails

Target: Fc Receptor, IgG, Low Affinity IV (FCGR4)

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 9E9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Antigendetails

Target: Fc Receptor, IgG, Low Affinity IV (FCGR4)

Andere Bezeichnung: CD16.2 (FCGR4 Produkte)

Synonyme: 4833442P21Rik antikoerper, CD16-2 antikoerper, FcgRIV antikoerper, FcgammaRIV antikoerper, Fcgr3a antikoerper, Fcrl3 antikoerper, Fc receptor, IgG, low affinity IV antikoerper, Fcgr4 antikoerper

Hintergrund: FcγRIV, also known as CD16-2, is an intermediate-affinity activating receptor for IgG2a and IgG2b. It is expressed on peripheral blood leukocytes, spleen, thymus, colon, and the intestine. CD16.2 is the mouse homolog of human Fcγ RIIIA. CD16.2 is a low-affinity IgE receptor for all allotypes and the ligation of FcγRIV by antigen-IgE immune complexes promotes macrophage-mediated phagocytosis and is involved in lung inflammation.