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Macrophage Mannose Receptor 1 Antikörper
MRC1
Reaktivität: Human
MA
Wirt: Maus
Monoclonal
15-2
unconjugated
Produktnummer ABIN2664383
Produktdetails anti-Macrophage Mannose Receptor 1 Antikörper
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Target
Alle Macrophage Mannose Receptor 1 (MRC1) Antikörper anzeigen
Macrophage Mannose Receptor 1 (MRC1)
(Mannose Receptor, C Type 1 (MRC1))
Reaktivität
Alle Reaktivitäten für Macrophage Mannose Receptor 1 Antikörper
Human
Wirt
Alle Wirte für Macrophage Mannose Receptor 1 Antikörper
Maus
Klonalität
Alle Klonalitäten für Macrophage Mannose Receptor 1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für Macrophage Mannose Receptor 1 Antikörper
Dieser Macrophage Mannose Receptor 1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Macrophage Mannose Receptor 1 Antikörper
Multiplex Assay (MA)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
15-2
Isotyp
IgG1 kappa
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu Macrophage Mannose Receptor 1
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Target
Macrophage Mannose Receptor 1 (MRC1)
(Mannose Receptor, C Type 1 (MRC1))
Andere Bezeichnung
CD206 (MRC1 Produkte )
Synonyme
CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mrc1 antikoerper, MGC86525 antikoerper, MRC1 antikoerper, MRC1L-A antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, mannose receptor C-type 1 L homeolog antikoerper, mediator of replication checkpoint 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper, mrc1.L antikoerper, mrc1 antikoerper
Hintergrund
Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.
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