CD207 Antikörper

Produktnummer ABIN2664388

Produktdetails anti-CD207 Antikörper

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Intracellular Flow Cytometry (ICFC)

Kreuzreaktivität: Cynomolgus

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 10E2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207 (CD207 Produkte)

Synonyme: CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper

Hintergrund: CD207, also known as Langerin, is a 40 kD type II transmemberane cell glycoprotein which belongs to C-type lectin with mannose binding specificity. It is predominantly expressed on Langerhans cells and induces the formation of Birbeck granules, the Langerhans cell hallmark organelle. It is also found on several other subtypes of dendritic cells, such as dermal CD103-positive dendritic cells and splenic CD8-positive dendritic cells. Langerin is generally thought to be involved in antigen processing. Recently, it has been found that HIV captured by Langerin was internalized into Birbeck granule and degraded, which results in inhibition of HIV-1 infection and subsequent transmission.