RGD1311074 antikoerper, 2310016B05Rik antikoerper, Clm9 antikoerper, D11Ertd736e antikoerper, CLM-9 antikoerper, CLM9 antikoerper, NEPMUCIN antikoerper, TREM-4 antikoerper, TREM4 antikoerper, Cd300 molecule-like family member G antikoerper, CD300 molecule like family member G antikoerper, CD300 molecule like family member g antikoerper, triggering receptor expressed on myeloid cells 4 antikoerper, Cd300lg antikoerper, CD300LG antikoerper, Trem4 antikoerper
Hintergrund
CD300LG, also known as nepmucin (a not expressed in Peyer's patches mucin), is a member of the CD300 antigen like family. It is a 50-95 kD glycoprotein with one IgV like domain and one mucin like domain and four isoforms are produced by alternative splicing. Nepmucin is expressed on high endothelial venules (HEV) from lymph nodes, but is absent on HEV from the Peyer's patches. CD300LG mediates lymphocyte adhesion through the intraction of its Ig domain with ICAM-1 and rolling on HEVs through the interaction of its mucin like domain with L-selectine. Also, it may play a role in the molecular transcytosis across the capillary endothelium.