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- Target Alle CD40 Antikörper anzeigen
- CD40
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD40 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität
- Pavian, Schimpanse, Cynomolgus, Rhesusaffen, Squirrel Monkey (Saimiri spec.)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 5C3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD40 Primärantikörper
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anti-CD40 (CD40) (AA 26-187) antibody
CD40 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD40 (CD40) antibodyCD40 Reaktivität: Human FACS, IHC, IF, StM, DNA Mic Wirt: Maus Monoclonal C40-1605 unconjugated
anti-CD40 (CD40) (AA 21-193) antibodyCD40 Reaktivität: Human FACS, WB, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 4E1B9 unconjugated
anti-CD40 (CD40) (AA 29-107) antibodyCD40 Reaktivität: Human FACS, ELISA, IHC, StM, Coat Wirt: Maus Monoclonal C40-2383 unconjugated
anti-CD40 (CD40) (C-Term) antibodyCD40 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD40 (CD40) (AA 71-187) antibodyCD40 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 41-CD40 unconjugated
anti-CD40 (CD40) (AA 1-360) antibodyCD40 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD40 (CD40) (Extracellular Domain) antibodyCD40 Reaktivität: Human FACS, IHC, St Wirt: Maus Monoclonal 5C3 unconjugated
anti-CD40 (CD40) antibody (FITC)CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal HI40a FITC
anti-CD40 (CD40) antibodyCD40 Reaktivität: Human FACS, IHC, IP, Act Wirt: Kaninchen Chimeric G28-5 unconjugated Recombinant Antibody
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD40
- Andere Bezeichnung
- CD40 (CD40 Produkte)
- Synonyme
- Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper
- Hintergrund
- CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
- Pathways
- NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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