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IL12 Antikörper
IL12
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
7B12
unconjugated
Produktnummer ABIN2665102
Produktdetails anti-IL12 Antikörper
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Target
Alle IL12 Antikörper anzeigen
IL12
(Interleukin 12 (IL12))
Reaktivität
Alle Reaktivitäten für IL12 Antikörper
Human
Wirt
Alle Wirte für IL12 Antikörper
Maus
Klonalität
Alle Klonalitäten für IL12 Antikörper
Monoklonal
Konjugat
Alle Konjugate für IL12 Antikörper
Dieser IL12 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL12 Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
7B12
Isotyp
IgG1
Top Product
Discover our top product IL12 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu IL12
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Target
IL12
(Interleukin 12 (IL12))
Andere Bezeichnung
IL-12 (IL12 Produkte )
Synonyme
CLMF antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12 antikoerper, LOC100217488 antikoerper, IL-12p35 antikoerper, Il-12a antikoerper, Ll12a antikoerper, p35 antikoerper, IL12p40 antikoerper, IL12B antikoerper, IL-12 p35 antikoerper, interleukin 12B antikoerper, interleukin 12A antikoerper, interleukin 12b antikoerper, interleukin 12a antikoerper, Interleukin 12 level antikoerper, IL12B antikoerper, IL12A antikoerper, Il12b antikoerper, Il12a antikoerper, IL12 antikoerper, il12a antikoerper
Hintergrund
Bioactive IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. The disulfide-linked p40 homodimer can bind to IL-12 receptors and antagonize the activities of bioactive IL-12. The 7B12 antibody reacts with human IL-12 p70 heterodimer, but shows no reactivity with IL-12 p35 or p40 monomer. The 7B12 has high affinity to human IL-12 p70 heterodimer.
Pathways
JAK-STAT Signalweg , TLR Signalweg , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation , Cancer Immune Checkpoints , Inflammasome
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