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Siglec H Antikörper

Reaktivität: Maus ICFC Wirt: Ratte Monoclonal 551 unconjugated
Produktnummer ABIN2665359
  • Target Alle Siglec H Produkte
    Siglec H
    Reaktivität
    Maus
    Wirt
    • 14
    Ratte
    Klonalität
    • 14
    Monoklonal
    Konjugat
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Siglec H Antikörper ist unkonjugiert
    Applikation
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Produktmerkmale
    The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    551
    Isotyp
    IgG1, IgG1 kappa
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Siglec H
    Abstract
    Siglec H Produkte
    Synonyme
    6430529G09Rik antikoerper, Siglec-H antikoerper, sialic acid binding Ig-like lectin H antikoerper, Siglech antikoerper
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