FLT4 Antikörper
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- Target Alle FLT4 Antikörper anzeigen
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser FLT4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- AFL4
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product FLT4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
- Andere Bezeichnung
- VEGFR-3 (FLT4 Produkte)
- Synonyme
- FLT41 antikoerper, LMPH1A antikoerper, PCL antikoerper, VEGFR3 antikoerper, AI323512 antikoerper, Chy antikoerper, Flt-4 antikoerper, VEGFR-3 antikoerper, Vegfr3 antikoerper, cb1059 antikoerper, fms related tyrosine kinase 4 antikoerper, FMS-like tyrosine kinase 4 antikoerper, fms-related tyrosine kinase 4 antikoerper, FLT4 antikoerper, Flt4 antikoerper, flt4 antikoerper
- Hintergrund
- VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.
- Pathways
- RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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