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CD213alpha2 Antikörper

Reaktivität: Human FACS, IF Wirt: Maus Monoclonal 47 unconjugated
Produktnummer ABIN2665962
  • Target
    CD213alpha2
    Reaktivität
    Human
    Wirt
    • 4
    Maus
    Klonalität
    • 4
    Monoklonal
    Konjugat
    • 2
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Marke
    Ultra-LEAF™
    Aufreinigung
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    Klon
    47
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Konservierungsmittel
    Azide free
    Handhabung
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD213alpha2
    Hintergrund
    CD213α2, also known as IL13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13R α2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα 1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes, and activated B cells. However, its presence on the cell surface is highly regulated. CD213α2 is also expressed in various types of cancer which makes it an attractive therapeutic target.
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