CD300a Antikörper
-
- Target Alle CD300a (CD300A) Antikörper anzeigen
- CD300a (CD300A)
-
Reaktivität
- Maus
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD300a Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Marke
- Ultra-LEAF™
- Aufreinigung
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
-
Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Klon
- TX41
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CD300A Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Konservierungsmittel
- Azide free
- Handhabung
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- CD300a (CD300A)
- Andere Bezeichnung
- CD300a (CD300A Produkte)
- Synonyme
- CD300L-B1 antikoerper, CD300A antikoerper, clm8 antikoerper, B230315M08Rik antikoerper, Clm8 antikoerper, LMIR1 antikoerper, MAIR-I antikoerper, MAIR-Ia antikoerper, MMAC8 antikoerper, Pigr4 antikoerper, mcpir1 antikoerper, CLM-8 antikoerper, CMRF-35-H9 antikoerper, CMRF-35H antikoerper, CMRF35-H antikoerper, CMRF35-H9 antikoerper, CMRF35H antikoerper, CMRF35H9 antikoerper, IGSF12 antikoerper, IRC1 antikoerper, IRC1/IRC2 antikoerper, IRC2 antikoerper, IRp60 antikoerper, CD300 molecule like family member g antikoerper, CD300a molecule antikoerper, CMRF35-like molecule 8 antikoerper, CD300A molecule antikoerper, Cd300a molecule antikoerper, CD300LG antikoerper, CD300A antikoerper, LOC483289 antikoerper, clm8 antikoerper, Cd300a antikoerper
- Hintergrund
- CD300 receptors are a group of type I transmembrane proteins, which belong to the Ig superfamily. In mice, nine members have been reported with different nomenclature systems, such as myeloid-associated Ig-like receptor (MAIR), leukocyte mono-Ig-like receptor (LMIR), DC-derived Ig-like receptor (DIgR), and CMRF-35-like molecule (CLM). The CD300 Molecules act as either activating or inhibitory receptors through interactions with adaptor molecules, such as PAD12, DAP10, and FcRγ. CD300a is an inhibitory receptor that is mainly expressed on peripheral eosinophils, mast cells, neutrophils, dendritic cells, macrophages, and some B cells. Cross-linking CD300a by an antibody can induce phosphorylation of tyrosine residues in the cytoplasmic domain, which results in recruitment of phosphatases SHIP, SHP1 and SHP2 and inhibition of cell activation.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-