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BCL11B Antikörper

BCL11B Reaktivität: Human FACS Wirt: Ratte Monoclonal 25B6 unconjugated
Produktnummer ABIN2666299
  • Target Alle BCL11B Antikörper anzeigen
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Reaktivität
    • 42
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Human
    Wirt
    • 42
    • 1
    • 1
    Ratte
    Klonalität
    • 34
    • 10
    Monoklonal
    Konjugat
    • 28
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BCL11B Antikörper ist unkonjugiert
    Applikation
    • 28
    • 15
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Maus, Zebrafisch
    Kreuzreaktivität (Details)
    Mouse, Zebrafish
    Aufreinigung
    Protein G affinity purified.
    Klon
    25B6
    Isotyp
    IgG
    Top Product
    Discover our top product BCL11B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Hepes-buffered solution, pH 7.5, 0.02 % Sodium azide .
    Lagerung
    4 °C
    Informationen zur Lagerung
    Upon receipt, store undiluted between 2°C and 8°C.
  • Target
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Andere Bezeichnung
    Bcl11b (BCL11B Produkte)
    Hintergrund
    The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.
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