GPR177/WLS Antikörper
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- Target Alle GPR177/WLS (WLS) Antikörper anzeigen
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GPR177/WLS Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Klon
- YJ5
- Isotyp
- IgG1
- Top Product
- Discover our top product WLS Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Upon receipt, store undiluted between 2°C and 8°C.
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- Target
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
- Andere Bezeichnung
- Wntless (WLS Produkte)
- Hintergrund
- Wnt signaling plays important roles in embryonic development and cancer formation. Wntless (GPR177) is a putative G-protein coupled receptor that regulates Wnt's trafficking and secretion. It can regulate the expression, subcellular location, binding, and organelle-specific association of Wnt proteins. In mammals, Wntless is mainly expressed in submucosa, muscle, ganglia, and nerve cells of the large intestines. Overexpression of Wntless may activate the NF-κB signaling pathway in cancer cells.
- Pathways
- WNT Signalweg
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