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Rpb1 CTD Antikörper (pSer5, Ser5)

Reaktivität: Human WB, IF, ICC, ChIP, ChIP-seq, IP Wirt: Ratte Monoclonal 3E8 unconjugated
Produktnummer ABIN2668541
  • Target Alle Rpb1 CTD Produkte
    Rpb1 CTD (RNA Polymerase II CTD)
    Bindungsspezifität
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    pSer5, Ser5
    Reaktivität
    • 24
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 10
    • 9
    • 5
    Ratte
    Klonalität
    • 15
    • 9
    Monoklonal
    Konjugat
    • 24
    Dieser Rpb1 CTD Antikörper ist unkonjugiert
    Applikation
    • 24
    • 17
    • 14
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq), Immunoprecipitation (IP)
    Aufreinigung
    None
    Immunogen
    This RNA pol II CTD pSer5 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 5.
    Klon
    3E8
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 μg/μL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Lagerung
    -80 °C
    Informationen zur Lagerung
    Antibodies in solution can be stored at -80 °C for 2 years.
    Haltbarkeit
    6 months
  • Harlen, Trotta, Smith, Mosaheb, Fuchs, Churchman: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).

    Ramos, Wijetunga, McLellan, Suzuki, Greally: "DNA demethylation by 5-aza-2'-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences." in: Epigenetics & chromatin, Vol. 8, pp. 11, (2015) (PubMed).

    Eifler, Shao, Bartholomeeusen, Fujinaga, Jäger, Johnson, Luo, Krogan, Peterlin: "Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 468-78, (2014) (PubMed).

    Hintermair, Heidemann, Koch, Descostes, Gut, Gut, Fenouil, Ferrier, Flatley, Kremmer, Chapman, Andrau, Eick: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." in: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).

    Chapman, Heidemann, Albert, Mailhammer, Flatley, Meisterernst, Kremmer, Eick: "Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7." in: Science (New York, N.Y.), Vol. 318, Issue 5857, pp. 1780-2, (2007) (PubMed).

  • Target
    Rpb1 CTD (RNA Polymerase II CTD)
    Andere Bezeichnung
    RNA Pol II CTD (Rpb1 CTD Produkte)
    Molekulargewicht
    240 kDa
    Gen-ID
    5430
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