Rpb1 CTD Antikörper (pSer5, Ser5)
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- Target Alle Rpb1 CTD Produkte
- Rpb1 CTD (RNA Polymerase II CTD)
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Bindungsspezifität
- pSer5, Ser5
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Rpb1 CTD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq), Immunoprecipitation (IP)
- Aufreinigung
- None
- Immunogen
- This RNA pol II CTD pSer5 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 5.
- Klon
- 3E8
- Isotyp
- IgG2a
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 μg/μL
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Antibodies in solution can be stored at -80 °C for 2 years.
- Haltbarkeit
- 6 months
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-
Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).
: "DNA demethylation by 5-aza-2'-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences." in: Epigenetics & chromatin, Vol. 8, pp. 11, (2015) (PubMed).
: "Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 468-78, (2014) (PubMed).
: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." in: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).
: "Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7." in: Science (New York, N.Y.), Vol. 318, Issue 5857, pp. 1780-2, (2007) (PubMed).
: "
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Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).
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- Target
- Rpb1 CTD (RNA Polymerase II CTD)
- Andere Bezeichnung
- RNA Pol II CTD (Rpb1 CTD Produkte)
- Molekulargewicht
- 240 kDa
- Gen-ID
- 5430
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