MLL/KMT2A Antikörper (AA 161-356)

Produktnummer ABIN2668648

Produktdetails anti-MLL/KMT2A Antikörper

Target: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Bindungsspezifität: AA 161-356

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MLL/KMT2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)

Aufreinigung: Protein G Chromatography

Immunogen: This MLL1 antibody was raised against a recombinant protein corresponding to amino acids 161-356 of mouse MLL1.

Klon: N4-4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -20 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-MLL/KMT2A Antikörper (ABIN2668648)

Aguilar-Arnal, Katada, Orozco-Solis, Sassone-Corsi: "NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1." in: Nature structural & molecular biology, Vol. 22, Issue 4, pp. 312-8, (2015) (PubMed).

Jin, Zhao, Yi, Nakata, Kalota, Gewirtz: "c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis." in: The Journal of clinical investigation, Vol. 120, Issue 2, pp. 593-606, (2010) (PubMed).

Details zu MLL/KMT2A

Target: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Andere Bezeichnung: MLL / HRX (MLL Produkte)

Synonyme: ALL-1 antikoerper, CXXC7 antikoerper, HRX antikoerper, HTRX1 antikoerper, MLL antikoerper, MLL/GAS7 antikoerper, MLL1A antikoerper, TET1-MLL antikoerper, TRX1 antikoerper, WDSTS antikoerper, 6430520K01 antikoerper, All1 antikoerper, Cxxc7 antikoerper, Mll antikoerper, Mll1 antikoerper, mKIAA4050 antikoerper, lysine methyltransferase 2A antikoerper, lysine (K)-specific methyltransferase 2A antikoerper, KMT2A antikoerper, Kmt2a antikoerper

Molekulargewicht: 440 kDa

Gen-ID: 4297

Pathways: Warburg Effekt