EIF2AK2 Antikörper (AA 329-551)
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- Target Alle EIF2AK2 Antikörper anzeigen
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Bindungsspezifität
- AA 329-551
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser EIF2AK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- EIF2AK2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli.
- Klon
- 6H3A10
- Isotyp
- IgG1
- Top Product
- Discover our top product EIF2AK2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Andere Bezeichnung
- EIF2AK2 (EIF2AK2 Produkte)
- Synonyme
- PKR antikoerper, pkr antikoerper, EIF2AK2 antikoerper, DKFZp469K1934 antikoerper, EIF2AK1 antikoerper, PRKR antikoerper, 2310047A08Rik antikoerper, 4732414G15Rik antikoerper, AI467567 antikoerper, AI747578 antikoerper, Pkr antikoerper, Prkr antikoerper, Tik antikoerper, eukaryotic translation initiation factor 2 alpha kinase 2 antikoerper, eukaryotic translation initiation factor 2-alpha kinase 2 antikoerper, EIF2AK2 antikoerper, eif2ak2 antikoerper, Eif2ak2 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Aliases: PKR, PRKR, EIF2AK1
- Molekulargewicht
- 62kDa
- Gen-ID
- 5610
- HGNC
- 5610
- UniProt
- P19525
- Pathways
- DNA Reparatur, ER-Nucleus Signaling, Hepatitis C
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