TIE1 Antikörper (AA 385-607)
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- Target Alle TIE1 Antikörper anzeigen
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Bindungsspezifität
- AA 385-607
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TIE1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Verwendungszweck
- TIE1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
- Klon
- 8D12D2
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Andere Bezeichnung
- TIE1 (TIE1 Produkte)
- Synonyme
- JTK14 antikoerper, TIE antikoerper, D430008P04Rik antikoerper, tie-1 antikoerper, tyrosine kinase with immunoglobulin like and EGF like domains 1 antikoerper, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antikoerper, tyrosine-protein kinase receptor Tie-1 antikoerper, endothelium-specific receptor tyrosine kinase 1 antikoerper, TIE1 antikoerper, Tie1 antikoerper, CpipJ_CPIJ018933 antikoerper, tie1 antikoerper
- Hintergrund
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Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Aliases: TIE, JTK14
- Molekulargewicht
- 125kDa
- Gen-ID
- 7075
- HGNC
- 7075
- UniProt
- P35590
- Pathways
- RTK Signalweg
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