Reacts with the poliovirus receptor 2 (PRR2) protein. PRR2 is a cell surface molecule homologous to the poliovirus receptor (PVR/CD155). It is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The PRR2 gene encodes for two mRNA isoforms, a short form of 3.0 kb (hPRR2α) and a long form of 4.4 kb (hPRR2δ). Both are widely expressed in human tissues, including hematopoietic cells. PRR2 is also expressed on endothelial cells, at the intercellular junctions of adjacent cells. It has been suggested that PRR2 may play a role in the regulation of hematopoietic/endothelial cell interaction. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of HL-60 cell line analyzed by flow cytometry. Second step staining with Cat. No. 555988.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C.
Lopez, Aoubala, Jordier, Isnardon, Gomez, Dubreuil: "The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule." in: Blood, Vol. 92, Issue 12, pp. 4602-11, (1999) (PubMed).
Eberlé, Dubreuil, Mattei, Devilard, Lopez: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." in: Gene, Vol. 159, Issue 2, pp. 267-72, (1995) (PubMed).
Target
PVRL2
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))