Reacts with DEC-205, a 205 kDa transmembrane protein with C-type lectin external domains, present on dendritic cells (DC) and some epithelia. It is being described as a multilectin receptor for adsorptive endocytosis. MG38 antibody reacted with mature monocyte-derived DC and also with B cells, monocytes and weakly on T cells and NK cells. Antibody MG38 is useful for the study of DC development. Profile of CD205 (DEC-205), clone MG38, reactivity on monocyte-derived cultured dendritic cells analyzed by flow cytometry. Second step staining with FITC Goat Anti-Mouse IgG/IgM (Cat. No. 555988).
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C.
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Kato, Neil, Fearnley, McLellan, Vuckovic, Hart: "Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells." in: International immunology, Vol. 12, Issue 11, pp. 1511-9, (2000) (PubMed).
Kato, Neil, Clark, Morris, Sorg, Hart: "cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells." in: Immunogenetics, Vol. 47, Issue 6, pp. 442-50, (1998) (PubMed).