CD51/CD61 Antikörper
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- Target Alle CD51/CD61 (ITGAV/ITGB3) Antikörper anzeigen
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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Reaktivität
- Human, Kaninchen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD51/CD61 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Marke
- BD Pharmingen™
- Produktmerkmale
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Reacts with the integrin αvβ3 heterodimeric complex (CD51/CD61), which is expressed in high amounts on osteoclasts, endothelial cells, melanoma cells, and in very low amounts on platelets. This antibody has been reported to cross-react with chicken and rabbit, but not with rat, αvβ3. The integrin αvβ3, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin, and its binding to some ligands has been reported to be inhibited by the 23C6 mAb. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of M21 (melanoma) cells analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD51/CD61 - Purified - Clone 23C6 - Isotype Mouse IgG1, κ - Reactivity Hu, Rab - 0.1 mg - Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Klon
- 23C6
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product ITGAV/ITGB3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 4°C.
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Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins." in: The Journal of biological chemistry, Vol. 268, Issue 22, pp. 16737-45, (1993) (PubMed).
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Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins." in: The Journal of biological chemistry, Vol. 268, Issue 22, pp. 16737-45, (1993) (PubMed).
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- Target
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Andere Bezeichnung
- CD51/CD61 (ITGAV/ITGB3 Produkte)
- Synonyme
- CD51 antikoerper, MSK8 antikoerper, VNRA antikoerper, VTNR antikoerper, integrin subunit alpha V antikoerper, ITGAV antikoerper
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