CD59 Antikörper
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- Target Alle CD59 Antikörper anzeigen
- CD59
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD59 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Marke
- BD Pharmingen™
- Produktmerkmale
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Reacts with CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of glycosylphosphatidylinositol (GPI) anchor-defective mutant cell line analyzed on a FACScan Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchor protein analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD59 - Purified - Clone p282 (H19) - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg - Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Klon
- P282
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CD59 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 4°C.
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Membrane defence against complement lysis: the structure and biological properties of CD59." in: Immunologic research, Vol. 12, Issue 3, pp. 258-75, (1994) (PubMed).
: "CD58 and CD59 molecules exhibit potentializing effects in T cell adhesion and activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 3, pp. 672-7, (1992) (PubMed).
: "CD59 molecule: a second ligand for CD2 in T cell adhesion." in: European journal of immunology, Vol. 22, Issue 11, pp. 2943-7, (1992) (PubMed).
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Membrane defence against complement lysis: the structure and biological properties of CD59." in: Immunologic research, Vol. 12, Issue 3, pp. 258-75, (1994) (PubMed).
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- Target
- CD59
- Andere Bezeichnung
- CD59 (CD59 Produkte)
- Synonyme
- 16.3A5 antikoerper, 1F5 antikoerper, EJ16 antikoerper, EJ30 antikoerper, EL32 antikoerper, G344 antikoerper, HRF-20 antikoerper, HRF20 antikoerper, MAC-IP antikoerper, MACIF antikoerper, MEM43 antikoerper, MIC11 antikoerper, MIN1 antikoerper, MIN2 antikoerper, MIN3 antikoerper, MIRL antikoerper, MSK21 antikoerper, p18-20 antikoerper, Cd59a antikoerper, Cd59b antikoerper, MACIP antikoerper, CD59 molecule (CD59 blood group) antikoerper, CD59 molecule antikoerper, CD59 antikoerper, Cd59 antikoerper
- Pathways
- Komplementsystem
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