OPRD1 Antikörper (AA 81-180) (Biotin)

Produktnummer ABIN2690092

Produktdetails anti-OPRD1 Antikörper (Biotin)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Bindungsspezifität: AA 81-180

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRD1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Spezifität: This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79 % non-contiguous sequence similarity.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Andere Bezeichnung: Delta-type opioid receptor (OPRD1 Produkte)

Synonyme: OPRD antikoerper, DOR-1 antikoerper, Nbor antikoerper, mDOR antikoerper, opioid receptor delta 1 antikoerper, opioid receptor, delta 1 antikoerper, OPRD1 antikoerper, Oprd1 antikoerper

Hintergrund:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gen-ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus