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METTL14 Antikörper (AA 21-120) (Biotin)

METTL14 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN2690236
  • Target Alle METTL14 Antikörper anzeigen
    METTL14 (Methyltransferase Like 14 (METTL14))
    Bindungsspezifität
    • 14
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser METTL14 Antikörper ist konjugiert mit Biotin
    Applikation
    • 21
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Mettl14
    Isotyp
    IgG
    Top Product
    Discover our top product METTL14 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    METTL14 (Methyltransferase Like 14 (METTL14))
    Andere Bezeichnung
    Mettl14 (METTL14 Produkte)
    Synonyme
    RGD1304822 antikoerper, G430022H21Rik antikoerper, mKIAA1627 antikoerper, zgc:77296 antikoerper, methyltransferase like 14 antikoerper, methyltransferase like 14 L homeolog antikoerper, Mettl14 antikoerper, mettl14.L antikoerper, METTL14 antikoerper, mettl14 antikoerper
    Hintergrund

    Synonyms: mKIAA1627, G430022H21Rik, N6-adenosine-methyltransferase subunit METTL14, Methyltransferase-like protein 14, Mettl14, Kiaa1627

    Background: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop (By similarity). M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (PubMed:24394384).

    Gen-ID
    210529
    UniProt
    Q3UIK4
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