ZFYVE9 Antikörper (AA 71-170) (Biotin)

Produktnummer ABIN2690281

Produktdetails anti-ZFYVE9 Antikörper (Biotin)

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Bindungsspezifität: AA 71-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFYVE9 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SARA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ZFYVE9

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Andere Bezeichnung: SARA (ZFYVE9 Produkte)

Synonyme: CG15667 antikoerper, Dmel\\CG15667 antikoerper, SARA antikoerper, dSARA antikoerper, sara antikoerper, NSP antikoerper, Madhip antikoerper, SMADIP antikoerper, E030027L17 antikoerper, MADHIP antikoerper, Smad anchor for receptor activation antikoerper, zinc finger, FYVE domain containing 9 antikoerper, zinc finger FYVE-type containing 9 antikoerper, Sara antikoerper, Zfyve9 antikoerper, ZFYVE9 antikoerper

Hintergrund:

Synonyms: NSP, SARA, MADHIP, SMADIP, PPP1R173, Zinc finger FYVE domain-containing protein 9, Mothers against decapentaplegic homolog-interacting protein, Madh-interacting protein, Novel serine protease, Receptor activation anchor, hSARA, Smad anchor for receptor activation, ZFYVE9

Background: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Gen-ID: 9372

UniProt: O95405

Pathways: Protein targeting to Nucleus