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CD3 Antikörper

GMP Grade CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal OKT3 unconjugated
Produktnummer ABIN2704232
  • Target Alle CD3 Antikörper anzeigen
    CD3
    Reaktivität
    • 213
    • 101
    • 33
    • 20
    • 14
    • 10
    • 8
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 256
    • 51
    • 19
    • 13
    • 8
    Maus
    Klonalität
    • 337
    • 6
    Monoklonal
    Konjugat
    • 97
    • 40
    • 33
    • 27
    • 25
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD3 Antikörper ist unkonjugiert
    Applikation
    • 298
    • 94
    • 64
    • 57
    • 45
    • 42
    • 41
    • 24
    • 18
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Produktmerkmale
    CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
    Aufreinigung
    Purified
    Reinheit
    >95 %
    Güteklasse
    GMP Grade
    Immunogen
    Human peripheral blood lymphocytes
    Klon
    OKT3
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD3 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    CD3
    Andere Bezeichnung
    CD3 (CD3 Produkte)
    Synonyme
    CD3 antikoerper, AI504783 antikoerper, CD3epsilon antikoerper, T3e antikoerper, cd3-gamma antikoerper, cd3g antikoerper, cd3g-a antikoerper, cd3g/d antikoerper, cd3gd antikoerper, t3g antikoerper, CD3e molecule antikoerper, CD3d molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, CD3g molecule S homeolog antikoerper, CD3E antikoerper, CD3D antikoerper, Cd3e antikoerper, cd3g.S antikoerper
    Hintergrund
    CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
    NCBI Accession
    NM_000733
    UniProt
    P07766
    Pathways
    T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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