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p53 Antikörper

GMP Grade TP53 Reaktivität: Human WB Wirt: Maus Monoclonal PAB122 unconjugated
Produktnummer ABIN2704417
  • Target Alle p53 (TP53) Antikörper anzeigen
    p53 (TP53) (Tumor Protein P53 (TP53))
    Reaktivität
    • 863
    • 259
    • 216
    • 116
    • 50
    • 35
    • 33
    • 19
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 648
    • 231
    • 6
    • 2
    • 1
    Maus
    Klonalität
    • 602
    • 285
    • 1
    Monoklonal
    Konjugat
    • 488
    • 43
    • 39
    • 25
    • 22
    • 14
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p53 Antikörper ist unkonjugiert
    Applikation
    • 698
    • 334
    • 249
    • 219
    • 194
    • 146
    • 125
    • 124
    • 119
    • 68
    • 54
    • 35
    • 18
    • 17
    • 13
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Anti-p53 Unconjugated Antibody
    Produktmerkmale
    p53, a DNA-binding, oligomerization domain- and transcription activation domaincontaining tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.
    Aufreinigung
    Purified
    Reinheit
    >95 %
    Güteklasse
    GMP Grade
    Immunogen
    SV40-transformed, 3T3 clone 4 mouse cells
    Klon
    PAB122
    Isotyp
    IgG2b, kappa
    Top Product
    Discover our top product TP53 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    p53 (TP53) (Tumor Protein P53 (TP53))
    Andere Bezeichnung
    p53 (TP53 Produkte)
    Synonyme
    BCC7 antikoerper, LFS1 antikoerper, P53 antikoerper, TRP53 antikoerper, p53 antikoerper, Trp53 antikoerper, brp53 antikoerper, drp53 antikoerper, etID22686.5 antikoerper, fb40d06 antikoerper, wu:fb40d06 antikoerper, zgc:111919 antikoerper, Tp53 antikoerper, bbl antikoerper, bfy antikoerper, bhy antikoerper, p44 antikoerper, tp53 antikoerper, Xp53 antikoerper, TP53 antikoerper, tumor protein p53 antikoerper, cellular tumor antigen p53 antikoerper, transformation related protein 53 antikoerper, tumor protein p53 L homeolog antikoerper, TP53 antikoerper, CpipJ_CPIJ002758 antikoerper, Tp53 antikoerper, tp53 antikoerper, Trp53 antikoerper, tp53.L antikoerper
    NCBI Accession
    NM_000546
    UniProt
    P04637
    Pathways
    p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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