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FGFR2 Antikörper

FGFR2 Reaktivität: Human WB, FACS, IF Wirt: Maus Monoclonal 5F7 unconjugated
Produktnummer ABIN2717921
  • Target Alle FGFR2 Antikörper anzeigen
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Reaktivität
    • 136
    • 71
    • 50
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 123
    • 12
    • 1
    Maus
    Klonalität
    • 115
    • 21
    Monoklonal
    Konjugat
    • 57
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGFR2 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 55
    • 47
    • 40
    • 29
    • 17
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
    Produktmerkmale
    Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1
    Aufreinigung
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cell.
    Klon
    5F7
    Isotyp
    IgG2a
    Top Product
    Discover our top product FGFR2 Primärantikörper
  • Applikationshinweise
    WB 1:2000, IF 1:100, FLOW 1:100
    Kommentare

    The concentration of the product may vary between diferrent lots.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Andere Bezeichnung
    FGFR2 (FGFR2 Produkte)
    Synonyme
    FGFR2 antikoerper, FGFR2IIIb antikoerper, bek antikoerper, bfr-1 antikoerper, cd332 antikoerper, cek3 antikoerper, cfd1 antikoerper, ect1 antikoerper, fgfr-2 antikoerper, jws antikoerper, k-sam antikoerper, kgfr antikoerper, tk14 antikoerper, tk25 antikoerper, xfgfr2 antikoerper, DKFZp469H1521 antikoerper, BBDS antikoerper, BEK antikoerper, BFR-1 antikoerper, CD332 antikoerper, CEK3 antikoerper, CFD1 antikoerper, ECT1 antikoerper, JWS antikoerper, K-SAM antikoerper, KGFR antikoerper, TK14 antikoerper, TK25 antikoerper, AU043015 antikoerper, AW556123 antikoerper, Bek antikoerper, Fgfr-2 antikoerper, Fgfr-7 antikoerper, Fgfr7 antikoerper, KGFRTr antikoerper, svs antikoerper, FGF-R antikoerper, fgfr72IIIb antikoerper, FGFR antikoerper, fc56c05 antikoerper, wu:fc56c05 antikoerper, fibroblast growth factor receptor 2 antikoerper, fibroblast growth factor receptor 2 L homeolog antikoerper, FGFR2 antikoerper, LOC100084641 antikoerper, fgfr2 antikoerper, Fgfr2 antikoerper, fgfr2.L antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Molekulargewicht
    89.7 kDa
    Gen-ID
    2263
    NCBI Accession
    NM_000141
    HGNC
    2263
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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