FGFR2 Antikörper
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- Target Alle FGFR2 Antikörper anzeigen
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FGFR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cell.
- Klon
- 5F7
- Isotyp
- IgG2a
- Top Product
- Discover our top product FGFR2 Primärantikörper
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- Applikationshinweise
- WB 1:2000, IF 1:100, FLOW 1:100
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- Andere Bezeichnung
- FGFR2 (FGFR2 Produkte)
- Synonyme
- FGFR2 antikoerper, FGFR2IIIb antikoerper, bek antikoerper, bfr-1 antikoerper, cd332 antikoerper, cek3 antikoerper, cfd1 antikoerper, ect1 antikoerper, fgfr-2 antikoerper, jws antikoerper, k-sam antikoerper, kgfr antikoerper, tk14 antikoerper, tk25 antikoerper, xfgfr2 antikoerper, DKFZp469H1521 antikoerper, BBDS antikoerper, BEK antikoerper, BFR-1 antikoerper, CD332 antikoerper, CEK3 antikoerper, CFD1 antikoerper, ECT1 antikoerper, JWS antikoerper, K-SAM antikoerper, KGFR antikoerper, TK14 antikoerper, TK25 antikoerper, AU043015 antikoerper, AW556123 antikoerper, Bek antikoerper, Fgfr-2 antikoerper, Fgfr-7 antikoerper, Fgfr7 antikoerper, KGFRTr antikoerper, svs antikoerper, FGF-R antikoerper, fgfr72IIIb antikoerper, FGFR antikoerper, fc56c05 antikoerper, wu:fc56c05 antikoerper, fibroblast growth factor receptor 2 antikoerper, fibroblast growth factor receptor 2 L homeolog antikoerper, FGFR2 antikoerper, LOC100084641 antikoerper, fgfr2 antikoerper, Fgfr2 antikoerper, fgfr2.L antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
- Molekulargewicht
- 89.7 kDa
- Gen-ID
- 2263
- NCBI Accession
- NM_000141
- HGNC
- 2263
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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