TUBG1 Antikörper
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- Target Alle TUBG1 Antikörper anzeigen
- TUBG1 (Tubulin, gamma 1 (TUBG1))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TUBG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Tubulin gamma antibody detects endogenous levels of Tubulin gamma protein. (region surrounding Phe414)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product TUBG1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- TUBG1 (Tubulin, gamma 1 (TUBG1))
- Andere Bezeichnung
- TUBG1 / Tubulin gamma 1 (TUBG1 Produkte)
- Hintergrund
- TUB4, the gene for Saccharomyces cerevisiae gamma-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. gamma Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. gamma Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. gamma Tubulin associates with spindle body components Spc97 and Spc98 to form the gamma Tubulin complex. The budding yeast gamma Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of gamma Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the gamma Tubulin complex. 2D gel analysis indicates five isoforms of gamma Tubulin. The phosphorylation of gamma Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.Synonyms: GCP-1, Gamma-1-tubulin, Gamma-tubulin complex component 1, Tubulin gamma-1 chain
- Molekulargewicht
- approx. 55 kDa
- Gen-ID
- 7283
- NCBI Accession
- NP_001061
- UniProt
- P23258
- Pathways
- Microtubule Dynamics, M Phase
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