FMR1 Antikörper (AA 36-279)
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- Target Alle FMR1 Antikörper anzeigen
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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Bindungsspezifität
- AA 36-279
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Reaktivität
- Human, Maus, Ratte, Hund, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FMR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.
- Klon
- 1C6
- Isotyp
- IgG1
- Top Product
- Discover our top product FMR1 Primärantikörper
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- Applikationshinweise
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).
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A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).
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- Target
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- Andere Bezeichnung
- FMR1 (FMR1 Produkte)
- Synonyme
- AT24755 antikoerper, BcDNA:GM08679 antikoerper, CG6203 antikoerper, Dmel\\CG6203 antikoerper, EP(3)3517 antikoerper, FMR antikoerper, FMR1 antikoerper, FMRP antikoerper, FMRp antikoerper, FXR antikoerper, Fmrp antikoerper, cg6203 antikoerper, dFMR antikoerper, dFMR1 antikoerper, dFMRP antikoerper, dFXR antikoerper, dFXR1 antikoerper, dFXRP antikoerper, dFmr1 antikoerper, dFmrp antikoerper, dfmr antikoerper, dfmr1 antikoerper, dfxr antikoerper, dfxr1 antikoerper, dmfr1 antikoerper, fmr antikoerper, fmr1 antikoerper, FRAXA antikoerper, POF antikoerper, POF1 antikoerper, zFMR1 antikoerper, Fmr-1 antikoerper, CG6203 gene product from transcript CG6203-RC antikoerper, fragile X mental retardation 1 antikoerper, fragile X mental retardation syndrome 1 antikoerper, Fmr1 antikoerper, FMR1 antikoerper, fmr1 antikoerper
- Hintergrund
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
- Molekulargewicht
- 71 kDa
- Gen-ID
- 2332
- NCBI Accession
- NM_002024
- HGNC
- 2332
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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