14-3-3 theta Antikörper
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- Target Alle 14-3-3 theta (YWHAQ) Antikörper anzeigen
- 14-3-3 theta (YWHAQ)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser 14-3-3 theta Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of 14-3-3 θ protein. (region surrounding Gln67)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product YWHAQ Primärantikörper
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- Applikationshinweise
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- 14-3-3 theta (YWHAQ)
- Andere Bezeichnung
- 14-3-3 Protein theta (YWHAQ Produkte)
- Synonyme
- 14-3-3 antikoerper, 14-3-3t antikoerper, 1c5 antikoerper, hs1 antikoerper, 1C5 antikoerper, HS1 antikoerper, 2700028P07Rik antikoerper, AA409740 antikoerper, AU021156 antikoerper, R74690 antikoerper, ywhaq antikoerper, ywhaq2 antikoerper, wu:fa91b01 antikoerper, wu:fb02e12 antikoerper, wu:fb36f06 antikoerper, wu:fk86h02 antikoerper, ywhaq1 antikoerper, ywhaz antikoerper, zgc:55499 antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta S homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a antikoerper, 14-3-3 protein theta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b antikoerper, YWHAQ antikoerper, ywhaq antikoerper, Ywhaq antikoerper, ywhaq.S antikoerper, ywhaqa antikoerper, ywhaqb antikoerper
- Hintergrund
- 14-3-3 proteins regulate many cellular processes relevant to cancer biology,notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activitiesSynonyms: 14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1, YWHAQ
- Molekulargewicht
- approx. 28 kDa
- Gen-ID
- 10971
- NCBI Accession
- NP_006817
- UniProt
- P27348
- Pathways
- Apoptose, Myometrial Relaxation and Contraction
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