CD83 Antikörper
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- Target Alle CD83 Antikörper anzeigen
- CD83
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD83 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects endogenous levels of CD83 protein. (region surrounding Pro130)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product CD83 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C one month or (in aliquots) at -20 °C for longer.
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- Target
- CD83
- Andere Bezeichnung
- CD83 (CD83 Produkte)
- Synonyme
- BL11 antikoerper, HB15 antikoerper, CD83 molecule antikoerper, CD83 antigen antikoerper, Cd83 antikoerper, CD83 antikoerper
- Hintergrund
- CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anticancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells.Synonyms: B-cell activation protein, Cell surface protein HB15, HB15
- Molekulargewicht
- approx. 23, 45 kDa
- Gen-ID
- 9308
- NCBI Accession
- NP_001035370
- UniProt
- Q01151
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