PDE4B Antikörper
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- Target Alle PDE4B Antikörper anzeigen
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PDE4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
- Klon
- 1D12
- Isotyp
- IgG1
- Top Product
- Discover our top product PDE4B Primärantikörper
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- Applikationshinweise
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." in: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
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AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." in: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
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- Target
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- Andere Bezeichnung
- PDE4B (PDE4B Produkte)
- Synonyme
- dpde4 antikoerper, pde4b5 antikoerper, pdeivb antikoerper, Dpde4 antikoerper, R74983 antikoerper, dunce antikoerper, PDE4/IVb antikoerper, Pde4B1 antikoerper, Pde4B2 antikoerper, Pde4B3 antikoerper, Pde4B4 antikoerper, DPDE4 antikoerper, PDE4B5 antikoerper, PDEIVB antikoerper, phosphodiesterase 4B antikoerper, phosphodiesterase 4B, cAMP specific antikoerper, phosphodiesterase 4B S homeolog antikoerper, pde4b antikoerper, PDE4B antikoerper, Pde4b antikoerper, pde4b.S antikoerper
- Hintergrund
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molekulargewicht
- 83.2 kDa
- Gen-ID
- 5142
- NCBI Accession
- NM_002600
- HGNC
- 5142
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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