RASSF1 Antikörper (AA 1-341)
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- Target Alle RASSF1 Antikörper anzeigen
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Bindungsspezifität
- AA 1-341
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RASSF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 1-341 of human RASSF1(NP_009113) produced in HEK293T cell.
- Klon
- 9F5
- Isotyp
- IgG1
- Top Product
- Discover our top product RASSF1 Primärantikörper
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- Applikationshinweise
- WB 1:2000, IF 1:100, FLOW 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Andere Bezeichnung
- RASSF1 (RASSF1 Produkte)
- Synonyme
- RASSF1 antikoerper, zgc:92505 antikoerper, wu:fc17f02 antikoerper, zgc:112224 antikoerper, 123F2 antikoerper, NORE2A antikoerper, RASSF1A antikoerper, RDA32 antikoerper, REH3P21 antikoerper, AA536941 antikoerper, AU044980 antikoerper, Rassf1A antikoerper, Rassf1B antikoerper, Rassf1C antikoerper, NPR2-like, GATOR1 complex subunit antikoerper, Ras association (RalGDS/AF-6) domain family 1 antikoerper, Ras association domain family member 1 antikoerper, putative rassf1 antikoerper, Ras association domain family member 1 L homeolog antikoerper, Ras association (RalGDS/AF-6) domain family member 1 antikoerper, NPRL2 antikoerper, rassf1 antikoerper, RASSF1 antikoerper, Smp_157340 antikoerper, rassf1.L antikoerper, Rassf1 antikoerper
- Hintergrund
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Molekulargewicht
- 38.6 kDa
- Gen-ID
- 11186
- NCBI Accession
- NM_007182
- HGNC
- 11186
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