PAX6 Antikörper
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- Target Alle PAX6 Antikörper anzeigen
- PAX6 (Paired Box 6 (PAX6))
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Reaktivität
- Human, Maus, Ratte, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PAX6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Human PAX6
- Aufreinigung
- Protein G purified
- Immunogen
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Recombinant human PAX6 protein.
Type of Immunogen: Recombinant protein - Klon
- PAX6-496
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PAX6 Primärantikörper
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- Applikationshinweise
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Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)
Usage: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. ELISA: Order BSA-free antibody format for coating. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2°C to 8°C.
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- Target
- PAX6 (Paired Box 6 (PAX6))
- Andere Bezeichnung
- PAX6 (PAX6 Produkte)
- Synonyme
- pax6 antikoerper, an2 antikoerper, mgda antikoerper, wagr antikoerper, pax-6 antikoerper, pax6a antikoerper, xpax6 antikoerper, XLPAX6 antikoerper, MGC52531 antikoerper, PAX-6 antikoerper, AN antikoerper, AN2 antikoerper, D11S812E antikoerper, MGDA antikoerper, WAGR antikoerper, Pax-6 antikoerper, pax6b antikoerper, 1500038E17Rik antikoerper, AEY11 antikoerper, Dey antikoerper, Gsfaey11 antikoerper, Sey antikoerper, PAXZF-A antikoerper, Pax6.1 antikoerper, cb280 antikoerper, fc20e07 antikoerper, pax-a antikoerper, pax[zf-a] antikoerper, paxzfa antikoerper, wu:fc20e07 antikoerper, zfpax-6a antikoerper, zfpax-6b antikoerper, paired box 6 antikoerper, paired box 6 L homeolog antikoerper, paired box 6 S homeolog antikoerper, paired box 6a antikoerper, PAX6 antikoerper, pax6 antikoerper, Pax6 antikoerper, pax6.L antikoerper, pax6.S antikoerper, pax6a antikoerper
- Hintergrund
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Name/Gene ID: PAX6
Synonyms: PAX6, AN2, D11S812E, MGDA, Oculorhombin, Paired box 6, Paired box homeotic gene-6, AN, Aniridia type II protein, WAGR, Paired box protein Pax-6 - Gen-ID
- 5080
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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